Dude, who even knows.
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I suppose one cause of all the aerobic energy issues could be that something in the chain is limiting the amount of oxygen to make it into my bloodstream to react with blood sugar in the first place. Early in the plague when we had waves of death in Boston and NYC you heard about effects on the alveolar tissue. In trying to figure things out I got a sphygmomanometer and blood sugar testing strips but nothing to measure oxygenation, though.
But I mean you can't just take enough creatine you completely sideline aerobic and don't need to breathe, can you? Can...